20 on Brand Guest Cameos The Big Bang Theory Ran

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The Big Bang Theory helped shape mainstream TV and brought new life to complicated terms like “Brobdingnagian Brobdingnagian” and other big words not often used in English. Executive producers Chuck Lorre and Bill Prady created the American television sitcom, and both served as head writers on the series, along with Steven Molaro. The Big Bang Theory aired in September 2007 and continued until May 2019, running for 12 impressive seasons.

The TV show initially revolves around five main characters: Sheldon Cooper (played by Jim Parsons) and Leonard Hofstadter (played by Johnny Galecki), both physicists at Caltech. Their socially awkward friends and colleagues, Howard Wolowitz (played by Simon Helberg), and Raj Koothrappali (played by Kunal Nayyar), join them. Penny (Kaley Cuoco), an aspiring actress and waitress, lives across the hall from the duo and, in later seasons, develops feelings for Leonard. Later, neuroscientist Amy Fowler (Mayim Bialik) joins the show as Sheldon’s love interest and subsequent wife.

Many famous people made appearances on the long-running show. Although most fans remember Bob Newhart’s portrayal of Professor Proton, many other stars you might have forgotten appeared throughout the series. 

1. Neil deGrasse Tyson

Neil deGrasse Tyson is a renowned American astrophysicist and influential scientific communicator. He appears as himself in the episode “The Apology Insufficiency,” seen by millions. Hysterically, Sheldon accuses Tyson of demoting Pluto from its planet status.

2. Stephen Hawking

Stephen Hawking was an acclaimed physicist whose work included the study of quantum gravity and quantum mechanics. In a 2012 episode, he appeared as Sheldon’s hero. 

3. Carrie Fisher

The late Star Wars queen Carrie Fisher also helped make this show a hit in an episode featuring guest James Earl Jones and Sheldon getting into mischief as they pranked Fisher during a late-night visit.

4. Buzz Aldrin

Buzz Aldrin appeared as himself on a fun episode when Wolowitz made his journey into space. The former American astronaut and pilot on the 1969 Apollo 11 mission ensured that a whole new generation of trick-or-treaters knew he was the second person to walk on the moon. 

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5. James Earl Jones

American actor and king of the smooth and deep voice, James Earl Jones sang karaoke with Sheldon and performed a version of “The Lion Sleeps Tonight,” a famous song from The Lion King.

6. Adam West 

The original Batman from the 1960s ABC series also made a guest appearance after Leonard and his friends talked the TV icon into attending one of Sheldon’s birthday parties.

7. Mark Hamill

Carrie Fisher wasn’t the only Star Wars cast member to guest star on the popular iconic TV show. Mark Hamill, who played Luke Skywalker in the sci-fi hit, also appeared to perform the nuptials at Amy and Sheldon’s wedding. 

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8. Katee Sackhoff

Katee Sackhoff played a role in Wolowitz’s dream as her alter-ego, Lieutenant Kara “Starbuck” Thrace, on the Sci-Fi Channel’s television series Battlestar Galactica.

9. Stan Lee

Comic book creator Stan Lee, responsible for the late X-Men, Avengers, and other superhero sagas, also made an appearance on the show. Howard, Sheldon, Leonard, and Raj,  huge fans of the comic book hero, met him, but make a mess out of things when they ask him to sign their comic books.

10. Danica McKellar

Danica McKellar is best known for her role as Winnie Cooper on The Wonder Years. McKellar is also a real-life mathematician and education advocate, and writer of New York Times bestsellers Kiss My Math and Math Doesn’t Suck. She plays a character named Abby, who goes on a date with Raj.

11. Billy Bob Thornton

In an episode of the eighth season, Hollywood A-lister Billy Bob Thornton played Dr. Oliver Lorvis, Penny’s creepy pharmaceutical client. Dr. Lorvis misunderstands the nature of their relationship and tries to initiate a romantic connection with Penny, but bonds with the guys instead.

Thornton brings his socially awkward character to life as he pursues romance with every woman he meets.

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12. Steve Wozniak

During the show’s fourth season, Apple co-founder Steve Wozniak guest stars as himself in an episode where Sheldon discovers he won’t live to see the day he can transfer his consciousness into a robot. This leads him to devise a plan to increase his lifespan via a mobile virtual presence device. Then, Sheldon has a funny run-in with Wozniak inside the Cheesecake Factory while controlling the device from his bedroom.

13. Bob Newhart

Veteran actor Bob Newhart performs as Arthur Jeffries aka Professor Proton, in a science TV show that Sheldon loves. However, the feelings aren’t mutual.

Newhart’s sharp wit and perfectly timed delivery make Professor Proton a recurring character on the show. Eventually, the two form a strange bond and share some touching moments. 

14. Regina King

Actress Regina King, best known as Brenda Jenkins in the television series 227, has also guested on The Big Bang Theory numerous times. King plays Janine Davis, Caltech’s Human Resources Administrator. Her position at the university often involves dealing with the gang’s crazy shenanigans.

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15. Laurie Metcalf

A longtime cast member on the sitcom Roseanne, Laurie Metcalf appeared on The Big Bang Theory as Sheldon’s mom. Metcalf also made several cameo appearances throughout the show, even on Sheldon’s wedding day.

16. Charlie Sheen 

Chuck Lorre and Charlie Sheen have collaborated on several successful projects, such as Two and a Half Men. That probably led to the larger-than-life actor’s cameo appearance on The Big Bang Theory in Season 2’s “The Griffin Equivalency” episode.

17. Joe Manganiello

Heartthrob and star of Magic Mike, Joe Manganiello makes a cameo appearance and joins guest stars Kevin Smith, Kareem Abdul-Jabbar, and Wil Wheaton for a fierce game of Dungeons and Dragons at William Shatner’s house. The fairytale match is a dream come true for Sheldon, of course!

18. Sarah Michelle Gellar

Buffy the Vampire Slayer star Sarah Michelle Gellar appeared as herself in the 2019 season finale. The actress gets smitten with Raj on a plane flight and later shows up as his date when the two attend Sheldon and Amy’s Nobel Prize ceremony.

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19. LeVar Burton

Actor and director LeVar Burton appears on The Big Bang Theory, playing a fictitious version of himself. Burton is best known for his role as Geordi La Forge in Star Trek: The Next Generation. The Reading Rainbow host appears on multiple episodes, including when he joins Sheldon and Amy as a guest star on their web series Fun with Flags.

20. Sara Gilbert

Another longtime Roseanne actor, Sara Gilbert made nine appearances on the show as Sheldon’s nemesis, Leslie Winkle. In one episode, Winkle ends up in a rebound relationship with Leonard Hofstadter, played by Johnny Galecki. This seems fitting, since Galecki played Gilbert’s boyfriend on Roseanne in the 1990s.

 

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